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KMID : 1038120140470050452
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Clinical Endoscopy
2014 Volume.47 No. 5 p.452 ~ p.454
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Esophageal Involvement of Pemphigus Vulgaris Associated with Upper Gastrointestinal Bleeding
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Chang Soo-Yun
Park Soo-Jung
Kim Sun-Wook
Jin Moo-Nyun
Lee Jung-Hee
Kim Hyun-Ju
Hong Sung-Pil
Kim Tae-Il
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Abstract
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Esophageal involvement of pemphigus vulgaris is rare, and when present, the most common presenting symptoms reported in the medical literature are odynophagia and dysphagia. Here, we present two cases of pemphigus vulgaris presenting with upper gastrointestinal hemorrhage because of esophageal involvement of the disease. In case 1, a 41-year-old female patient with a prior diagnosis of pemphigus vulgaris presented with hematemesis. Esophagogastroduodenoscopy showed diffuse mucosal exfoliation and oozing bleeding of the oropharynx and esophagus. The patient recovered after the administration of high-dose corticosteroids and immunosuppressants. In case 2, a 30-year-old female patient with known pemphigus vulgaris also presented with hematemesis, showing similar endoscopic findings to the first case. She also responded to the same treatment. Esophageal involvement of pemphigus vulgaris responds to high-dose corticosteroids and immunosuppressants. Thus, in patients with pemphigus vulgaris with signs or symptoms of upper gastrointestinal bleeding, an early endoscopy for the evaluation of esophageal involvement is beneficial.
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KEYWORD
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Pemphigus vulgaris, Esophageal involvement, Upper gastrointestinal bleeding
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